The Rhythm Effect

Neuroscientists have recently discovered that brain rhythms supporting memory and cognition are disrupted in people with Alzheimer’s disease. There is growing evidence that stimulating these brain waves at the right frequencies can improve memory and cognition, and even decrease amyloid plaques and tau tangles in the brain. 

Oscillo Biosciences has developed a digital therapeutic medical device based on this discovery—one that uses music in concert with synchronized light to restore brain function.

How Does it Work?

Our therapy works by combining music with a synchronized visual display to stimulate brain rhythms. The result is an activation of the whole brain, including memory, emotion, and reward centers.

Music engages the whole person. Unlike pharmaceuticals, music is natural, pleasant, and has no side effects. Neuroscience research shows that music stimulates brain rhythms at Delta, Theta, and Gamma frequencies. 

Synchronized light reinforces brain rhythms. Patients can choose their favorite music, increasing their compliance with the protocol. Our patented technology determines in real time which neural frequencies to reinforce. 

Music and synchronized light combine to produce a synergistic effect, potentially reaching parts of the brain that can’t be reached by sound or light alone. The experience is pleasant, in contrast to other forms of brain stimulation that use harsh sounds or direct transcranial stimulation.

Promising Benefits

Preliminary data points to improvement in many symptoms of Alzheimer’s disease.

Decrease in brain plaques and tangles

Improved memory, cognition and overall brain function

Reduced depression / improved mood

Reduced need for a variety of medications

Decrease in aggressive / distressed behaviors

Pain relief

Improved sleep

Promising Benefits

Research to date on music-based interventions and gamma stimulation shows no negative side effects and a host of promising benefits.

Improved memory, cognition and overall brain function

Decrease in amyloid plaques and tau tangles

Reduced depression / improved mood

Decrease in aggressive / distressed behaviors

Reduced need for medication

The Science

Brain Rhythms and Early Signs
Neuroscience researchers have observed disruptions in rhythmic brain activity in patients with dementia. Disruptions in brain activity in the Gamma-frequency range have been observed prior to the onset of cognitive impairment, and prior to the formation of plaque deposits associated with Alzheimer’s disease.

Music as Brain Stimulation
Neuroscientists have found that music activates and entrains brain rhythms, including rhythms in the Theta- and Gamma-frequency ranges. Music engages far more brain areas than simpler stimuli—areas that are well-preserved in Alzheimer’s. It naturally activates memory, emotion, and reward centers.

Gamma Rhythm Stimulation
Neuroscientists have also found that Gamma stimulation can produce changes in the brain at the molecular level, diminishing brain plaques, untangling neural networks, and improving the brain’s immune response.

These observations strongly suggest that if we can restore normal rhythmic activity throughout the brain, including rhythms in the Gamma band, we should be able to delay or even reverse the onset of dementia-related disorders like Alzheimer’s disease.

Music and Light
We know that we can stimulate brain rhythms auditorily (using sound) and visually (using light). At Oscillo Biosciences, we are marrying the power of music with a rhythmic visual experience to activate multiple areas of the brain at multiple frequencies, especially those involved in memory and cognition.

Know Your Brain Waves

Why Music?

Music is a world within itself
With a language we all understand.

—”Sir Duke” by Stevie Wonder

Music naturally stimulates brain rhythms and activates the whole brain, including emotion, memory, and reward centers. It stimulates the release of dopamine, the neurotransmitter associated with pleasure. Because it’s pleasurable, patients are more likely to use the therapy consistently.

Memory for music is preserved in mild to moderate, and in some cases, severe forms of Alzheimer’s disease. Familiar music, in particular, is deeply rooted in our conscious and unconscious brains, giving it the ability to awaken memories.

The Oscillo Biosciences Difference

A Fresh Approach

Pharmaceuticals have become the default answer for everything that ails us. At Oscillo Biosciences, we think it’s time to step away from the pill bottle, broaden our perspective and aim higher. 

Reaching the Person Inside

As humans, our very identities are imprinted in our memories. Our goal is to reawaken the human being within each patient.

Music + Light

Oscillo Biosciences is developing the only therapy that synchronizes music and light for a synergistic effect that reaches more areas of the brain than any other approach. 

Beyond Alzheimer’s

In addition to exploring the potential to delay or halt the onset of multiple Alzheimer’s disease biomarkers, we are looking into applications of rhythmic brain stimulation for disorders such as Parkinson’s disease, aphasia, dyslexia, and others.